A new study suggests that fish oil may be beneficial in adolescents and young adults who are at risk of developing psychotic disorders.
Some earlier evidence suggests that omega-3 fatty acids may have positive effects on various psychiatric illnesses, such as depression and schizophrenia. Since using antipsychotic medicine to prevent psychotic disorders is controversial, researchers set out to test the preventative effects of fish oil supplements, which are rich in fatty acids and have few side effects when used appropriately.
The study included 81 people who had low-level psychotic symptoms, transient psychotic symptoms, a schizophrenia-like personality disorder or a close relative with schizophrenia. The participants were 13-25 years old and all experienced a drastic decline in mental function within the last year.
The subjects were randomly assigned to receive fish oil supplements that contained 1.2 grams of omega-3 fatty acids or placebo daily for 12 weeks. The researchers monitored the participants for 40 weeks after treatment, and a total of 76 people completed the study.
By the end of the follow-up period, just five percent of people in the omega-3 group developed a psychotic illness compared to 28 percent in the placebo group. Additionally, people in the omega-3 group experienced significant improvements in psychotic symptoms and mental function.
Encouraging results. I am curious as to the proposed neuroprotective mechanism: is it inflammation? Or is this patient population at risk for nutritional deficiencies? Additionally, would the same results be achieved by dietary recommendations, such as increasing intake of foods known to be high in omega-3 fatty acids (e.g., flaxseed).